Shohei Ohtani launched his 12th home run of the season for the Los Angeles Angels in a 7-3 takedown of a Boston Red Sox lineup featuring Samurai Japan teammate Masataka Yoshida on Wednesday.
The two-way star gave the Halos a 5-0 lead with his solo shot to the opposite field in the bottom of the third inning at Angel Stadium.
The high fly ball was one of two home runs surrendered by Boston starter James Paxton (1-1), who also gave up a three-run shot to rookie shortstop Zach Neto in the second.
Mike Trout made it 7-1 to the Angels in the fourth with his 362nd career homer, a two-run blast that took him past Joe DiMaggio on the all-time home run list.
Trout and Ohtani both homered in the same game for the fourth time this season and the 26th time since they became teammates in 2018, according to MLB.com.
Ohtani finished 1-for-4, while fellow World Baseball Classic champion Yoshida also had a 1-for-4 outing after lining a fourth-inning double.
At Wrigley Field, Seiya Suzuki drove in one run and scored another to help the Chicago Cubs inflict a 4-2 loss on compatriot Kodai Senga and the New York Mets. Over five innings, Senga (4-3) allowed three runs on six hits and five walks, while striking out six.
Yusei Kikuchi (5-2) was also charged with the loss as his Toronto Blue Jays went down 7-3 at the Tampa Bay Rays. The Japanese southpaw fanned five over five innings, while giving up five runs on eight hits and a pair of walks.