Masahiro Tanaka allowed a grand slam in the New York Yankees' 5-2 defeat to the Chicago White Sox on Sunday and suffered his first loss of the season.

Tanaka (1-1) struck out six over his first three innings at Yankee Stadium, but loaded the bases in the fourth on a double and two walks. He gave up the Yankees' 2-0 lead when Tim Anderson belted a grand slam off the Japanese right-hander's go-to splitter.

The 30-year-old took the mound in the fifth but was pulled after letting two hits and a walk fill the bases a second time. Tanaka was tagged for five runs on seven hits and three walks.

Luke Voit and Aaron Judge drove in the Yankees' early runs against White Sox lefty Carlos Rodon (2-2), who struck out five and allowed three hits over six innings. Jose Abreu's sac fly in the fifth capped the scoring.

At Chase Field, Japanese reliever Yoshihisa Hirano allowed two runs in 2/3 inning of the Arizona Diamondbacks' 8-4 win over the San Diego Padres.