Shohei Ohtani went 2-for-5 with a three-run homer and two runs scored as the Los Angeles Angels came from behind twice to beat the Colorado Rockies 10-7 on Monday.

With the Angels trailing 2-0 in the fourth inning, Mike Trout singled in a run to halve the deficit before Ohtani stepped to the box.

The two-way phenom took a called strike from Colorado starter Jon Gray before launching a three-run go-ahead shot past the center-field wall.

DJ LeMahieu's grand slam in the eighth put the Rockies back on top, but Ohtani singled against Adam Ottavino in the bottom of the inning to help land the righty into a bases loaded jam.

Oh Seung Hwan took over the mound and stretched Eric Young Jr. into a full count, and the left fielder slugged a line drive to center to drive in Ohtani and Jefry Marte for an 8-7 lead.

A throwing error added the final two runs, and Ohtani was struck out by Oh to cap the five-run rally as the Angels batted around.

Before the game, Ohtani threw 50 pitches over three innings in his second simulated game since being injured and said he feels ready to pitch for the Angels again.

"I can go now. I don't feel any uncertainty," Ohtani said. "There are a lot of things you won't know until you throw at the major league level. There's not much else to notice at this stage."

The 24-year-old Japanese rookie is looking to make his first major league pitching start since June 6, a day before he received stem-cell and platelet-rich plasma injections to treat a right elbow injury.

Angels manager Mike Scioscia said Ohtani's progress will be evaluated throughout the week before the club determines the next step in his rehabilitation.

"The pitch count was great. He maintained his stuff all the way through the workout. Three ups," Scioscia said, according to MLB.com.

"There are so many positives you can take away from it. The velocity was really good. It's a step forward. We'll see how he's evaluated in the next couple of days and then what the next step is."

Ohtani went 4-1 with a 3.10 ERA in nine starts for the Angels before being sidelined with a Grade 2 sprain of the ulnar collateral ligament in his pitching elbow. He has been used exclusively as a hitter since he came off the disabled list on July 3.